Who's Who in Gerontology: Companies

• A

• Aelan Cell Technologies

  Biotech developing stem-cell therapies by removing age-related constraints on stem cell vitality, as well as epigenetic aging biomarkers under licence from the Buck Institute.

  More Details ›

• Aeovian

  Biopharmaceutical company aiming to discover, develop and commercialize innovative therapeutics for the treatment of rare and age-related diseases, specifically by targeting the mTORC1 pathway.

  More Details ›

• AgeX Therapeutics

  AgeX is developing stem-cell and cellular reprogramming therapies to regenerate tissues.

  More Details ›

• Alkahest

  Alkahest is a clinical stage biopharmaceutical company developing therapies for neurodegenerative and age-related diseases by targeting specific chronokines, the proteins that increase or decrease with age.

  More Details ›

• Alterity Therapeutics

  They are primarily focused on developing treatments for neurodegenerative diseases.

  More Details ›

• Altos Labs

  Biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine.

  More Details ›

• Antoxis

  Antoxis is developing therapeutic antioxidants for treatment of age-related diseases like Alzheimer disease.

  More Details ›

• Apollo Health Ventures

  They are an investment company that aims to develop interventions with the potential to prevent or reverse age-related diseases and extend healthy human lifespan.

  More Details ›
• B

• BIOAGE Labs

  A VC-backed biotech company aimed at finding drugs that extend healthspan using machine learning and biomarkers.

  More Details ›

• BioMarker Pharmaceuticals

  Their goal is to develop pharmaceuticals and other therapies for the treatment and prevention of age-related disease. Their research is largely based on caloric restriction and DNA microarrays.

  More Details ›

• BioViva

  Bioviva is a bioinformatics and R&D company that targets cellular aging by developing new gene therapies to regenerate cells, muscles and organs.

  More Details ›
• C

• Calico

  The mission of Google-backed Calico is to harness advanced technologies to increase our understanding of the biology that controls lifespan. They then aim to use that knowledge to devise interventions that enable people to lead longer and healthier lives.

  More Details ›

• Celularity

  Clinical-stage cell therapeutics company delivering allogeneic cellular therapies, engineered from the postpartum human placenta, in cancer immunotherapy and functional regeneration.

  More Details ›

• Centagen

  They are developing multi-path therapeutics for age-related disorders via activating adult stem cells.

  More Details ›

• ChromaDex

  Global bioscience company pioneering research on NAD+.

  More Details ›

• Chronos Therapeutics

  Company screening novel and repositioned drugs for the treatment of age-related conditions, particularly neurodegenerative diseases and osteoporosis.

  More Details ›

• Cleara Biotech

  Targeting cellular senescence to extend human healthspan at old age and to counteract therapy resistance in late stage cancer. Based on the work of Peter de Keizer.

  More Details ›

• CohBar

  Research and development of mitochondria based therapeutics for aging-related diseases and metabolic dysfunction, including non-alcoholic steatohepatitis, obesity, Type 2 diabetes, cancer, cardiovascular disease and CNS disorders.

  More Details ›
• E

• Elevian

  Elevian is developing a number of therapeutics that regulate GDF11 and other circulating factors, in order to restore the natural regenerative capacity of the body, addressing a root cause of age-associated diseases.

  More Details ›

• Elysium Health

  They offer an epigenetic age measurement as well as supplements to boost NAD+.

  More Details ›

• Everon Biosciences

  Everon is developing small molecules and immunotherapeutics to block or slow down age-related waste products or facilitate their removal, as well as an aging diagnostic platform.

  More Details ›
• F

• Five Alarm Bio

  They are developing a small molecule approach to boost the body defence to aging, based on a new understanding of how the chemical damage associated with age accumulates in cells.

  More Details ›
• G

• GeneCare Research Institute Co

  They are primarily focused on cancer and inflammation, but have some interests in aging.

  More Details ›

• Genescient

  Company employing evolutionary genomics and genetics to develop therapeutics that target diseases of aging.

  More Details ›

• GenSight Biologics

  Clinical-stage gene-therapy company discovering, developing and commercializing novel therapies for patients with severe retinal neurodegenerative diseases.

  More Details ›

• Gero

  Gero is a data-driven longevity company focused on the development of new treatments to combat the aging process and extend healthy human lifespans, primarily around the topic of stability and stress resistance of gene regulatory networks.

  More Details ›

• Geron

  The company's technology is largely centered around the telomeres and telomerase. They have interests in stem cells and cloning, but their main focus is on cancer.

  More Details ›

• Gerostate Alpha

  Pharmaceutical company that aims to develop breakthrough pharmaceuticals to mitigate and reduce the effects of aging.

  More Details ›

• Gordian Biotechnology

  Gordian is a therapeutics company pioneering a novel screening platform to radically increase the efficiency of development for complex diseases of aging.

  More Details ›
• H

• Human Longevity, Inc. (HLI)

  By focusing on genomics, informatics, and stem cell therapies, HLI aims to tackle aging and aging-related diseases.

  More Details ›
• I

• Ichor Therapeutics

  Ichor is a group of companies developing drugs to target various classes of molecular damage driving aging, including Lysoclear, Fox Bio, Antoxerene, Auctus Biologics.

  More Details ›

• Insilico Medicine

  They employ machine-learning techniques for drug discovery and repurposing for cancer and age-related diseases.

  More Details ›
• J

• Juvena Therapeutics

  Juvena plans to discover novel protein-based therapeutics that promote tissue regeneration in the elderly and treat various age-related diseases, combining proteomics and with machine-learning analysis of microscopy.

  More Details ›

• Juvenescence

  They create and partner with new companies with longevity-related therapeutics, aiming to develop therapies that will enable people worldwide to live longer, healthier lives.

  More Details ›

• Juvenon

  Juvenon develop and market nutritional supplements for healthy aging that aim to prevent the decay of mitochondria.

  More Details ›
• K

• Kizoo Technology Ventures

  KIZOO provides mentoring, seed and early-stage financing with a focus on rejuvenation biotech.

  More Details ›
• L

• L-Nutra

  Develops and produces fasting-mimicking diet products to enhance healthspan based on aging research by Valter Longo.

  More Details ›

• Legendary Pharmaceuticals

  They aim to develop drugs and therapies to prevent and treat age-related diseases. Their strategy is based on repairing and reversing progressive damage to mitochondria and lysosomes.

  More Details ›

• Libella Gene Therapeutics

  Libella aims to complete a human trial using AAV/hTERT to treat or significantly improve Alzheimer disease using telomerase gene therapy.

  More Details ›

• Life Biosciences

  Founded by David Sinclair, they aim to develop medicines for aging in its entirety by setting up several daughter companies focused on the hallmarks of aging.

  More Details ›

• Life Length

  Life Length provides services in telomere and telomerase measurement and diagnostics.

  More Details ›

• Longeveron

  Developing a cell-based therapy for aging frailty, Alzheimer disease, and metabolic syndrome.

  More Details ›

• Longevity Biotech

  Longevity Biotech is working to develop modulators of natural defense mechanisms in order to develop new therapeutic compounds.

  More Details ›

• Longevity Vision Fund

  Founded by longevity investor and visionary Sergey Young, they aim to make longevity accessible and affordable by funding life extension breakthroughs.

  More Details ›
• M

• Mitotech

  Development of pharmaceutical products based on mitochondria targeted antioxidants for treatment of age-related disorders, including dry eye.

  More Details ›
• N

• Navitor Pharmaceuticals

  Clinical-stage biotech focused on selective targeting of mTORC1 activators and inhibitors for different age- and non-age-related indications.

  More Details ›

• NeuroNascent, Inc

  Neuronascent is a small corporation that focuses on generating new neurons for reversing neurological disorders.

  More Details ›

• NewLimit

  NewLimit aims to treat age-related diseases to extend human healthspan. Their approach is based on using epigenetic reprogramming to unlock new treatments.

  More Details ›
• O

• Oisin Biotechnologies

  Oisin is developing a novel class of therapeutics, Proteo-Lipid Vehicles containing DNA, to kill senescent and cancer cells.

  More Details ›
• P

• Ponce de Leon Health

  Their first product, Rejuvant, is a dietary supplement, coupled with a non-invasive DNA methylation test to estimate biological aging.

  More Details ›

• Proteostasis Therapeutics

  Proteostasis Therapeutics develops drugs that control the body's protein homeostasis which could lead to therapies against genetic and degenerative disorders that include several age-related diseases.

  More Details ›
• R

• Rejuvenate Bio

  Developing treatments for animal aging and age-related diseases. Currently focusing on treating dog mitral valve disease with gene therapy.

  More Details ›

• Rejuvenate Biomed

  The company plans to repurpose safe and well tolerated prescription drugs that could impact the aging process.

  More Details ›

• Rejuveron Life Sciences AG

  Integrated biotechnology platform company that invests in people and ideas to develop therapies and technologies to improve healthy aging and prolong lifespan.

  More Details ›

• Retro Biosciences

  Retro Biosciences aim to extend healthy human lifespan. They are focused on cellular reprogramming, autophagy and plasma-inspired therapeutics.

  More Details ›

• Retrotope

  Retrotope focuses on the development of ways of controlling metabolic processes associated with oxidative stress, in particular neurodegenerative diseases.

  More Details ›
• S

• Sibelius

  They have a focus on screening natural compounds and nutraceuticals for their therapeutic benefits in treating age-related conditions. This is the sister company of Chronos Therapeutics.

  More Details ›

• Sierra Sciences

  Sierra Sciences is a biotechnology company whose long-term goal is to develop drugs and therapies that will cure and prevent human diseases associated with aging. Presently, they focus mainly on telomeres and telomerase.

  More Details ›

• Signum Biosciences

  Company developing therapies for neurodegenerative diseases such as Alzheimer's and Parkinson's disease by studying protein networks.

  More Details ›

• Siwa Therapeutics

  A pre-clinical stage company with a humanized monoclonal antibody, SIWA 318H, that selectively targets both senescent cells and cancer cells.

  More Details ›

• Spring Discovery

  A machine learning platform combined with cell- and tissue-based assays to accelerate experimentation for discovering anti-aging therapies.

  More Details ›
• T

• The Longevity Fund

  The Longevity Fund backs world class entrepreneurs developing therapeutic breakthroughs for age-related disease.

  More Details ›

• Turn Bio

  They focus on cellular reprogramming to address most of the hallmarks of aging and rejuvenate tissues. Initial candidate applications are osteoarthritis, skin damage, and sarcopenia.

  More Details ›
• U

• Underdog Pharmaceuticals

  The company is developing a novel class of cyclodextrins to target toxic forms of cholesterol in atherosclerosis.

  More Details ›

• Unity Biotechnology

  Unity is developing a number of therapies to eliminate senescent cells in order to halt, slow or reverse age-associated disease.

  More Details ›
• Y

• YouthBio Therapeutics

  They are developing gene therapies aimed at restoring more youthful epigenetic profiles.

  More Details ›